01841nas a2200157   4500008004100000245005500041210005500096260004200151300001400193520129400207100002801501700002201529700001901551700001701570856009601587       1999                        eng d00aApproach to standardizing MR image intensity scale0 aApproach to standardizing MR image intensity scale  aBellingham; WashingtonbSPIEc1999///  a595 - 6033 aDespite the many advantages of MR images, they lack a standardimage intensity scale. MR image intensity ranges and the meaning 
of intensity values vary even for the same protocol (P) and the 
same body region (D). This causes many difficulties in image 
display and analysis. We propose a two-step method for 
standardizing the intensity scale in such a way that for the 
same P and D, similar intensities will have similar meanings. In 
the first step, the parameters of the standardizing 
transformation are 'learned' from an image set. In the second 
step, for each MR study, these parameters are used to map their 
histogram into the standardized histogram. The method was tested 
quantitatively on 90 whole brain FSE T2, PD and T1 studies of MS 
patients and qualitatively on several other SE PD, T2 and SPGR 
studies of the grain and foot. Measurements using mean squared 
difference showed that the standardized image intensities have 
statistically significantly more consistent range and meaning 
than the originals. Fixed windows can be established for 
standardized imags and used for display without the need of per 
case adjustment. Preliminary results also indicate that the 
method facilitates improving the degree of automation of image 
segmentation.
1 aNyúl, László, Gábor1 aUdupa, Jayaram, K1 aMun, Seong, Ki1 aKim, Yongmin  uhttps://home.inf.u-szeged.hu/publication/approach-to-standardizing-mr-image-intensity-scale