@article {1004,
	title = {Brain atrophy in relapsing-remitting multiple sclerosis: Fractional volumetric analysis of gray matter and white matter},
	journal = {RADIOLOGY},
	volume = {220},
	year = {2001},
	note = {UT: 000170616700008ScopusID: 0034866802doi: 10.1148/radiol.2203001776},
	month = {2001///},
	pages = {606 - 610},
	abstract = {PURPOSE: To determine the fractional brain tissue volume changesin the gray matter and white matter of patients with relapsing-
remitting multiple sclerosis (MS) and to correlate these 
measurements with clinical disability and total lesion load. 
MATERIALS AND METHODS: Thirty patients with relapsing-remitting 
MS and 25 healthy control subjects underwent magnetic resonance 
imaging. Fractional brain tissue volumes (tissue volume relative 
to total intracranial volume) were obtained from the total 
segmented gray matter and white matter in each group and were 
analyzed. RESULTS: The fractional volume of white matter versus 
that of gray matter was significantly lower (-6.4\%) in patients 
with MS (P <.0001) than in control subjects. Neither gray matter 
nor white matter fractional volume measurements correlated with 
clinical disability in the patients with MS. CONCLUSION: Loss of 
brain parenchymal volume in patients with relapsing-remitting MS 
is predominantly confined to white matter. Analysis of 
fractional brain tissue volumes provides additional information 
useful in characterizing MS and may have potential in evaluating 
treatment strategies.
},
	isbn = {0033-8419}
}
@booklet {1076,
	title = {Brain Atrophy in Relapsing-Remitting Multiple Sclerosis: A Fractional Volumetric Analysis of Gray Matter and White Matter},
	year = {2000},
	month = {2000///}
}
@booklet {1074,
	title = {Magnetization Transfer Ratio Histogram Analysis of Normal Appearing Gray Matter and White Matter in MS},
	year = {2000},
	month = {2000///}
}
@conference {1018,
	title = {Tissue Characterization in Relapsing-remitting and Secondary-progressive MS via Magnetization Transfer Ratio},
	booktitle = {International Society for Magnetic Resonance in Medicine: Eight Scientific Meeting and Exhibition},
	year = {2000},
	month = {Apr 2000},
	pages = {1189},
	address = {Berkeley}
}
