01654nas a2200133   4500008004100000020001400041245012400055210006900179260001200248300001400260490000800274520119200282856004601474       2001                        eng d  a0033-841900aBrain atrophy in relapsing-remitting multiple sclerosis: Fractional volumetric analysis of gray matter and white matter0 aBrain atrophy in relapsingremitting multiple sclerosis Fractiona  c2001///  a606 - 6100 v2203 aPURPOSE: To determine the fractional brain tissue volume changesin the gray matter and white matter of patients with relapsing-
remitting multiple sclerosis (MS) and to correlate these 
measurements with clinical disability and total lesion load. 
MATERIALS AND METHODS: Thirty patients with relapsing-remitting 
MS and 25 healthy control subjects underwent magnetic resonance 
imaging. Fractional brain tissue volumes (tissue volume relative 
to total intracranial volume) were obtained from the total 
segmented gray matter and white matter in each group and were 
analyzed. RESULTS: The fractional volume of white matter versus 
that of gray matter was significantly lower (-6.4%) in patients 
with MS (P <.0001) than in control subjects. Neither gray matter 
nor white matter fractional volume measurements correlated with 
clinical disability in the patients with MS. CONCLUSION: Loss of 
brain parenchymal volume in patients with relapsing-remitting MS 
is predominantly confined to white matter. Analysis of 
fractional brain tissue volumes provides additional information 
useful in characterizing MS and may have potential in evaluating 
treatment strategies.
  uhttps://home.inf.u-szeged.hu/en/node/100400380nas a2200085   4500008004100000245012600041210006900167260001200236856004600248       2000                        eng d00aBrain Atrophy in Relapsing-Remitting Multiple Sclerosis: A Fractional Volumetric Analysis of Gray Matter and White Matter0 aBrain Atrophy in RelapsingRemitting Multiple Sclerosis A Fractio  c2000///  uhttps://home.inf.u-szeged.hu/en/node/107600361nas a2200085   4500008004100000245010700041210006900148260001200217856004600229       2000                        eng d00aMagnetization Transfer Ratio Histogram Analysis of Normal Appearing Gray Matter and White Matter in MS0 aMagnetization Transfer Ratio Histogram Analysis of Normal Appear  c2000///  uhttps://home.inf.u-szeged.hu/en/node/107400399nas a2200097   4500008004100000245011300041210006900154260002300223300000900246856004600255       2000                        eng d00aTissue Characterization in Relapsing-remitting and Secondary-progressive MS via Magnetization Transfer Ratio0 aTissue Characterization in Relapsingremitting and Secondaryprogr  aBerkeleycApr 2000  a1189  uhttps://home.inf.u-szeged.hu/en/node/1018