<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of the relationship between the metabolic status, the gastric emptying and the diabetic neuropathy</style></title><secondary-title><style face="normal" font="default" size="100%">EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING</style></secondary-title><short-title><style face="normal" font="default" size="100%">EUR J NUCL MED MOL I</style></short-title></titles><dates><year><style  face="normal" font="default" size="100%">2006</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2006</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">33</style></volume><pages><style face="normal" font="default" size="100%">S87</style></pages><isbn><style face="normal" font="default" size="100%">1619-7070</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><notes><style face="normal" font="default" size="100%">UT: 000202967400029SU: Suppl. 2</style></notes></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors></contributors><titles><title><style face="normal" font="default" size="100%">Dopamine transporter availability in medication free and in bupropion treated depression: a 99mTc-TRODAT-1 SPECT study.</style></title><secondary-title><style face="normal" font="default" size="100%">JOURNAL OF AFFECTIVE DISORDERS</style></secondary-title><short-title><style face="normal" font="default" size="100%">J AFFECT DISORDERS</style></short-title></titles><dates><year><style  face="normal" font="default" size="100%">2005</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2005</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">89</style></volume><pages><style face="normal" font="default" size="100%">115 - 123</style></pages><isbn><style face="normal" font="default" size="100%">0165-0327</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">BACKGROUND: Bupropion is thought to exert its antidepressive effect by blocking the dopamine transporter (DAT). The purpose of this study was to evaluate the DAT activity in depressed patients by means of 99mTc-TRODAT-1 SPECT in relation to the efficacy of bupropion treatment. METHODS: In 12 healthy controls and 16 depressed patients the baseline DAT activity was examined. Nine of the 16 patients went through an additional second SPECT investigation, after 4 weeks of bupropion treatment. RESULTS: In the depressed patients, the baseline DAT striatum-occipital ratio (SOR) (1.04+/-.36, mean+/-SD) was not significantly different from that in the control group (1.12+/-.33) (p&gt;.05). Correlation was found between baseline SOR and HAM-D score change (r=-.745, p=.02) of the bupropion treated patients. The average DAT occupancy due to the bupropion treatment was 20.84+/-27.7%. No significant correlation between the therapeutical effectiveness and the occupancy was observed. LIMITATIONS: One of the limiting factors of our study has been the lack of drug monitoring. CONCLUSIONS: In good agreement with other PET studies, we found 20.84% DAT occupancy during bupropion treatment. The lack of correlation between the efficacy of therapy and occupancy of DAT may raise the question as to whether other mechanisms are involved in the effect of bupropion.</style></abstract><issue><style face="normal" font="default" size="100%">1-3</style></issue><notes><style face="normal" font="default" size="100%">UT: 000234355500012ScopusID: 28444466222doi: 10.1016/j.jad.2005.08.016</style></notes></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors></contributors><titles><title><style face="normal" font="default" size="100%">Effects of bupropion in depression: a 99mTc-TRODAT SPECT study</style></title><secondary-title><style face="normal" font="default" size="100%">EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING</style></secondary-title><short-title><style face="normal" font="default" size="100%">EUR J NUCL MED MOL I</style></short-title></titles><dates><year><style  face="normal" font="default" size="100%">2004</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2004</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">31</style></volume><pages><style face="normal" font="default" size="100%">S228</style></pages><isbn><style face="normal" font="default" size="100%">1619-7070</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><notes><style face="normal" font="default" size="100%">UT: 000223419900123SU: Suppl. 2</style></notes></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of cerebral vasoreactivity by SPECT and transcranial Doppler sonography using the acetazolamide test.</style></title><secondary-title><style face="normal" font="default" size="100%">NUKLEARMEDIZIN-NUCLEAR MEDICINE</style></secondary-title><short-title><style face="normal" font="default" size="100%">NUKLEARMED-NUCL MED</style></short-title></titles><dates><year><style  face="normal" font="default" size="100%">1994</style></year><pub-dates><date><style  face="normal" font="default" size="100%">1994</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">33</style></volume><pages><style face="normal" font="default" size="100%">239 - 243</style></pages><isbn><style face="normal" font="default" size="100%">0029-5566</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">rCBF SPECT with 99mTc-HMPAO was performed prospectively in 29 patients (3 controls and 26 stroke patients) as well as TCD studies in 20 patients (3 controls and 17 stroke patients) before and after 1 g i.v. acetazolamide. The sensitivity of rCBF SPECT increased from 62% to 77% after acetazolamide provocation in stroke patients. In patients with a reversible neurological deficit, the sensitivity under resting conditions was 50% which increased to 71%, while in cases with a permanent deficit it increased from 75% to 83%. In the evaluation of the cerebrovascular reserve capacity the results of rCBF SPECT and TCD coincided in 91% of the hemispheres. The correlation was statistically significant.</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><notes><style face="normal" font="default" size="100%">UT: A1994QA82500003ScopusID: 0028641548</style></notes></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors></contributors><titles><title><style face="normal" font="default" size="100%">REST AND STRESS (ACETAZOLAMIDE) RCBF SPECT AND TRANSCRANIAL DOPPLER SONOGRAPHY STUDIES IN CEREBROVASCULAR DISORDERS</style></title><secondary-title><style face="normal" font="default" size="100%">EUROPEAN JOURNAL OF NUCLEAR MEDICINE</style></secondary-title><short-title><style face="normal" font="default" size="100%">EUR J NUCL MED</style></short-title></titles><dates><year><style  face="normal" font="default" size="100%">1992</style></year><pub-dates><date><style  face="normal" font="default" size="100%">1992///</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">19</style></volume><pages><style face="normal" font="default" size="100%">594</style></pages><isbn><style face="normal" font="default" size="100%">0340-6997</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><issue><style face="normal" font="default" size="100%">8</style></issue><notes><style face="normal" font="default" size="100%">UT: A1992JL49600094</style></notes></record></records></xml>